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Drug intolerance. Drug intolerance or drug sensitivity refers to an inability to tolerate the adverse effects of a medication, generally at therapeutic or subtherapeutic doses. Conversely, a patient is said to be "tolerating" a drug when they can tolerate its adverse effects. Some instances of drug intolerance are known to result from genetic ...
For example, a person who developed an allergy to a red dye will be allergic to any new drug which contains that red dye. A drug allergy is different from an intolerance. A drug intolerance, which is often a milder, non-immune-mediated reaction, does not depend on prior exposure.
While pseudoallergy and IgE-mediated allergy share some similarities in their clinical manifestations, pseudoallergy is not the same as common allergy or type 1 reactions. Pseudoallergy can be caused by a variety of medications through various pathways.
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to antigen. [1] [2] It is an abnormality in the immune system that causes immune diseases including allergies and autoimmunity .
Aspirin-exacerbated respiratory disease ( AERD ), also called NSAID-exacerbated respiratory disease ( N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti ...
Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD). Although less common than ICD, ACD is accepted to be the most prevalent form of immunotoxicity found in humans.
Multiple chemical sensitivity ( MCS ), also known as idiopathic environmental intolerances ( IEI ), is an unrecognized and controversial diagnosis characterized by chronic symptoms attributed to exposure to low levels of commonly used chemicals. [1] [2] Symptoms are typically vague and non-specific. They may include fatigue, headaches, nausea ...
Alcohol flush reaction is a condition in which a person develops flushes or blotches associated with erythema on the face, neck, shoulders, ears, and in some cases, the entire body after consuming alcoholic beverages. The reaction is the result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol, and ...
Food intolerance is more chronic, less acute, less obvious in its presentation, and often more difficult to diagnose than a food allergy. Symptoms of food intolerance vary greatly, and can be mistaken for the symptoms of a food allergy.
Salicylate intolerance is a form of food intolerance or of drug intolerance. Salicylate sensitivity is a pharmacological reaction, not a true IgE -mediated allergy . However, it is possible for aspirin to trigger non-allergic hypersensitivity reactions.