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Diagnosis of food intolerance can include hydrogen breath testing for lactose intolerance and fructose malabsorption, professionally supervised elimination diets, and ELISA testing for IgG-mediated immune responses to specific foods.
A radioallergosorbent test (RAST) is a blood test using radioimmunoassay test to detect specific IgE antibodies in order to determine the substances a subject is allergic to. This is different from a skin allergy test, which determines allergy by the reaction of a person's skin to different substances. [citation needed]
Allergy blood tests measure the presence of IgE antibodies to specific foods, pollens, mites, animals, insects and other environmental factors. (IgE, short for "immunoglobulin E", is the antibody that triggers food allergy symptoms.)
Diagnosis is usually based on a medical history, elimination diet, skin prick test, blood tests for food-specific IgE antibodies, or oral food challenge. [1] [2] Management involves avoiding the food in question and having a plan if exposure occurs. [2]
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A blood test for the specific antigen, IgE, to the alpha-gal carbohydrate, is commonly used for diagnosis in clinical practice. Typically, a level of 1% for IgE specific for alpha-gal out of total IgE in the body has been identified in patients with alpha-gal syndrome. [8]
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